S.A. Savko, A.P. Goncharov,
A.A. Lobanov, S.V. Andronov, A.R. Grabeklis
I.M. Sechenov First Moscow State
Medical University (Sechenov University),
Trubetskaya str. 8/2, Moscow, 119991, Russian Federation
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ABSTRACT. The
study of the elemental status of the population of the Sakhalin Oblast and the
Republic of Sakha (Yakutia) of the Russian Federation is necessary, due to the
sufficient contrast of these regions of the Far East in geochemical, climatic,
socio-economic characteristics and the assortment of local food products, aimed
at developing measures to adapt residents of the North to hypocomfort living
conditions.
The
aim is to study the elemental status of the male
population of the Sakhalin region and the Republic of Sakha (Yakutia) to
increase the adaptive potential and reduce the mortality of men of working age.
Materials
and methods. The content of chemical elements in the hair of
men aged 18-50 years, respectively, living in the Sakha Republic was studied
(Yakutia) (200 people) and the Sakhalin region (75 people). The analysis was
performed by inductively coupled plasma mass spectrometry (ICP-MS) on the basis
of the accredited laboratory of the ANO "Center for Biotic Medicine"
(Moscow; ISO 9001:2008 certificate 54Q10077 dated 21.05.2010).
Results.
Residents of the Sakhalin region are characterized by an increase in the
content of tin, boron, cobalt in their hair in combination with relatively low
levels of zinc and iron. The increase in the content of boron and cobalt in
hair may be due to the fact that there is a lot of boron in algae, cobalt – in
seafood. The relatively low content of lead, mercury, copper and cadmium in the
hair of Sakhalin residents is probably due to a higher standard of living and
medical care, quality of nutrition, consumption of alginates (algae), less
environmental pollution. Adult residents of the Republic of Sakha (Yakutia) are
characterized by an increased content of lead, cadmium, aluminum, chromium
pollutants in their hair, as well as macronutrients sodium and potassium in
combination with Se deficiency.
Conclusions. A
multi-element analysis of the hair of the male population of the Republic of
Sakha (Yakutia) and the Sakhalin region indicates the presence of an imbalance
among the adult population, which requires correction and consideration during
screening surveys of the population and the development of nutrition
improvement programs.
KEYWORDS: Sakhalin,
Yakutia, hair, selenium, mercury, aluminum, lead, cadmium, zinc, mass
spectrometry.