Trace Elements in Medicine (Moscow)
2018, 19(3): 18-23
ORIGINAL PAPERS

IDENTIFICATION OF DIETARY INTAKE OF TRACE ELEMENTS AT THE EARLY STAGE PARKINSON'S DISEASE

Y.V. Matyuk ¹, R.R. Bogdanov ¹, A.R. Bogdanov ²

¹Moscow Regional Scientific Research Clinical Institute n.a. M.F. Vladimirskiy, Schepkina str., 61/2, Moscow, 129110, Russia
²Federal Research Centre of Nutrition and Biotechnology, Ust'insky proezd, 2/14, 109240, Moscow, Russia

DOI: 10.19112/2413-6174-2018-19-3-18-23 

ABSTRACT. Objective. Investigation and identification of dietary intake of trace elements at the early stage Parkinson's disease (PD). Materials and methods. 43 patients with initial manifestations of PD stages 1 (according to the Hoehn and Yahr scale) were examined. For the identification of nutritional status a software program Nutrilogic was used. This program has been developed by the Federal Research Centre of Nutrition and Biotechnology. Results. Analysis of the nutritional status of the patients with initial manifestations of PD revealed the tendency to increase the dietary intake of iron, calcium and the tendency to decrease magnesium intake from food. Deficiency of fluorine, chlorine, iodine, silicon, molybdenum dietary intake was noticed. Moderate deficiency of manganese and zinc dietary intake was defined in patients with initial manifestations of PD. Conclusions. Moderate excess of dietary intake of iron, calcium and deficiency of manganese and zinc dietary intake conform to a potential role of these trace elements in the pathogenesis of PD. Discovered deficiency of fluorine, chlorine, iodine, silicon, molybdenum dietary intake requires the further identification of their role in the mechanisms of PD pathogenesis. The obtained results require the further study and create prerequisites for the possible additional correction of the deficiency of trace elements as a factor affecting the pathogenesis of PD.

KEYWORDS: Parkinson's disease, nutritional status, trace elements.