Trace Elements in Medicine (Moscow)
2017, 18(2): 10–16
ORIGINAL PAPER

THE REGIONAL FEATURES OF THE MICROELEMENT COMPOSITION OF BIOSUBSTRATES IN RESIDENTS OF THE NORTH-WEST REGION OF RUSSIA

S.G. Sukhanov1, A.L. Gorbachev2

1 Northern (Arctic) Federal University, Naberezhnaja Severnoj Dviny, 17, Arkhangelsk, 163002, Russia
2 North-Eastern State University, Portovaya str. 13, Magadan, 685000, Russia

DOI: 10.19112/2413-6174-2017-18-2-10-16 

ABSTRACT. Using atomic absorption spectrophotometry and flame photometry in organs and tissues (blood, amniotic fluid, hair, bone) in 242 adult men and women, and 122 newborn babies have been determined the levels of essential and toxic bioelements (Na, K, Mg, Ca, Cu, Zn, Fe, Cl, Pb, Mn, Fe, Al, Cd, S, Cr, Li, Ni, Sr, B, Ba, Bi, Co). Material for research was collected from different clinics of the Arkhangelsk region and the Komi Republic. The levels of the bioelements were compared to their physiological values in different organs and tissues. It was established that the complex of natural and anthropogenic extreme factors of the North-Western regions of Russia was accompanied by the development of microelementoses, including man-made disasters. Age-related changes in levels of bioelements included a significant decrease of copper and calcium levels. The imbalance of essential bioelements (copper, iron) in fe-to-placental unit was associated with the risk of anemia development in mother and fetus. Cumulative properties of bone tissue and age-related osteoporosis in adult population of the region create predisposition for development of musculoskeletal pathology. Increased aluminum, nickel and boron levels have led to adverse changes in bone tissue.

KEYWORDS: trace elements, biogeochemical province, intersystem relations.