Trace Elements in Medicine (Moscow)
2017, 18(1): 8–16
ORIGINAL PAPER

EFFECT OF TRACE ELEMENTS (I, CO, CU) ON COBALT METABOLISM

A.S. Ushakov1,2, Sh.G. Rakhmatullin, S.A. Miroshnikov2, T.N. Korolyova3

1 All-Russian Research Institute of Animal Physiology, Biochemistry and Nutrition, Russian Federation, p. Institute Borovsk, Kaluga region, 249013 Russia
2 All-Russian Research Institute of Beet Cattle Breeding, 9 Yanvarya str. 29, Orenburg 460000, Russia
3 Orenburg State University, Pobedy ave., 13, Orenburg, 460018 Russia
4 Central state medical Academy» The office of the President of the Russian Federation, Marshala Timoshenko str. 19, build 1A, Moscow 121359, Russia

DOI: 10.19112/2413-6174-2017-18-1-8-16 

ABSTRACT. Effect of I, Co, Cu salts supplementation to the stillage-based diet on the metabolism in Black-and-White bulls was studied. Using the principle of analogues on the basis of breed, age, sex and body weight, 3 groups of 10-month calves (290 kg body weight) were formed: control and two experimental ones (receiving I, Co, Cu salts) (n=28). To the diet of group I, trace elements (I, Co, Cu) were added according average norms for calves, to the group II the elements were not added, while the group III were supplemented with increased dosage of the elements. The analysis of metabolism changes under the different nutrient supply of the diet was achieved. Stable exchange of cobalt between blood and the digestive tract was demonstrated. The highest content of the element was found in omasum and small intestine, the lowest one was in rumen. The lowest accumulation levels of Co, especially in Co deficiency group, were found in back muscles, while the Co supplementation improved Co content. Concomitant use of I, Co, Cu salts in feeding of group III animals improved the thyroid activity and increased the cobalt level in the gland. The Co absorption significantly correlated with concentration of the element in the gastro-intestinal tract, i.e. in chyme. Thyroid gland, pancreas and liver were shown to possess high selective accumulation of cobalt.

KEYWORDS: metabolism, iodine, cobalt, copper, distillers grains.