ABSTRACT. The objective of the present study was to perform comparative analysis of hair levels of metals and metalloids in subjects from the cities of the northern part of the Moscow region in different distance from Moscow.
Materials and methods. The study enrolled 246 adult women aged 20−70 years old living in the cities Khimki (n = 81), Dolgoprudny (n = 72), Dmitrov (n = 45), and Dubna (n = 48) located in 19, 28, 65, and 116 km from Moscow. Assessment of hair metal and metalloid content in human hair was performed using inductively-coupled plasma massspectrometry.
Results. The obtained data demonstrate that the highest levels of arsenic, cadmium, iron, vanadium, and especially manganese were characteristic for women from Dubna. The highest cobalt content was observed in examinees living in Dmitrov. In contrast, hair copper content was the highest in women from Khimki. The results of non-parametric Kruskal-Wallis test and multiple linear regression demonstrate a significant increase in the levels of As, Cd, Co, Cr, Fe, V, and Mn with an increase in the distance from Moscow, whereas hair Cu content significantly decreased. No significant group difference in hair Hg, Ni, Pb, Sn, or Zn were observed. Correlation analysis demonstrated a strong association between hair content of As, Cd, Co, Cr, and V.
Conclusions. The results of the study demonstrate that the levels of As, Cd, Cr, Fe, Mn, and V increase in human hair in parallel with an increase in the distance from Moscow, reaching the highest contents in inhabitants of Dubna. Specific patterns of hair metal and metalloid accumulation may mediate different susceptibility of inhabitants of the cities of the Moscow region to environmental diseases, thus indicative of necessity for personalized approach in health management.
KEYWORDS: Moscow region, manganese, arsenic, ecology, pollution.
For citation: Skalny A.A., Korobeinikova T.V., Mazaletskaya A.L., Flerova E.A., Tinkov A.A. The levels of heavy metals and metalloids in hair of subjects living in the northern part of the Moscow region. Trace elemets in medicine. 2024;25(4):49−59. DOI: 10.19112/2413-6174-2024-25-4-49-59.
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