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Trace Elements in Medicine
International scientific and practical peer-reviewed journal
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BIOAVAILABILITY AND EFFECTIVENESS OF VITAMIN-MINERAL SUPPLEMENTS

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Bioavailability and effectiveness
of vitamin-mineral supplements


ABSTRACT


To replenish insufficient consumption of micronutrients and optimize the micronutrient status vitamin-mineral supplement (VMS) are used.

The purpose of the review is to identify factors influencing the effectiveness and bioavailability of vitamins and minerals when taking VMS.

Results. The bioavailability of a micronutrient is the proportion of it that is not only absorbed in the intestine, but is also used for physiological functions. When applied to micronutrient fortified foods and VMS, efficacy is largely equivalent to the bioavailability of the specific micronutrient contained within it, although ultimately reflects its bioavailability from the entire diet. The bioavailability of mineral elements depends on the chemical compound used, vitamins - on the vitamer included in the VMS, the nature of the carrier used, and the form of the VMS. To optimize the body's vitamin status by taking VMS containing vitamins in doses corresponding to 100% of the recommended daily intake, a fairly long period of time (up to several months) is required. After stopping additional use of VMS, a “wash-out” of vitamins occurs for one to several weeks, i.e blood concentration decreases and returns to the original state of deficiency.

Conclusion. Scientifically justified is the constant intake of VMS, and not individual micronutrients. The decisive factors for the effectiveness of VMS are the composition, doses of micronutrients approaching 100% of the recommended daily intake, the use of micronutrients with good bioavailability, and the duration of VMS administration.

KEYWORDS:  vitamin-mineral supplement, bioavailability, effectiveness, evaluation criteria.

For citation: Kodentsova V.M., Risnik D.V., Sharafetdinov Kh.Kh. Bioavailability and effectiveness of vitamin-mineral supplements. Trace elemets in medicine. 2024;25(1):3-15. DOI: 10.19112/2413-6174-2024-25-1-3-15