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Trace Elements in Medicine
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  3. Том 23 вып. 4
  4. THE ROLE OF MAGNESIUM, POTASSIUM, CALCIUM, ZINC AND LEAD IN THE DEVELOPMENT OF ESSENTIAL ARTERIAL HYPERTENSION IN CHILDREN

THE ROLE OF MAGNESIUM, POTASSIUM, CALCIUM, ZINC AND LEAD IN THE DEVELOPMENT OF ESSENTIAL ARTERIAL HYPERTENSION IN CHILDREN

A.F. Karaeva1, H.M. Malaev1, M.A. Ovchinnikova2, D.Z. Alieva1,
E.N. Agaeva1, S.O. Abdulkadyrova1, Sh.K. Salikhov3, M.A. Yahiyaev3

1 Dagestan State Medical University of the Ministry of Health of the Russian Federation,
Lenin Square, 1, Makhachkala, 367000, Russian Federation

2 I.M. Sechenov First Moscow State Medical University (Sechenov University),
Trubetskaya str., 8/2, Moscow, 119991, Russian Federation

3 Precaspian Institute of Biological Resources of the Dagestan Federal Research Centre of the RAS,
M. Gadzhieva St., 45, Makhachkala, 367000, Russian Federation

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ABSTRACT. Arterial hypertension (AH) is a severe pathology, the etiology has various prerequisites, and the exact causes have not been established. The aim of the study is to identify the relationship of geochemical factors (the content of magnesium, potassium, calcium, zinc, lead in soils and natural waters of the territory of the plain zone) with the prevalence of hypertension in the child population. The content of elements (magnesium, potassium, calcium, zinc, lead) was determined on the basis of the Laboratory of Biogeochemistry of the Caspian Institute of Biological Resources of the Dagestan Scientific Center of the Russian Academy of Sciences by atomic absorption spectroscopy. The prevalence rates of AH in the children's population of the lowland zone of Dagestan are calculated for 100,000 children (0-17 years old). The dependence of the pathology of hypertension of the children's population on the content of magnesium, potassium, calcium, zinc, lead in the soils and natural waters of Dagestan is determined – an increase in the number of patients with hypertension with an increase in the content of lead and a decrease in magnesium, potassium, calcium, zinc in the objects of the biosphere. When assessing the pathogenesis of hypertension in children, it is necessary to take into account the content of magnesium, potassium, calcium, zinc, and lead in soil and water, which affects the elemental status of the patient.

KEYWORDS: arterial hypertension, etiology, childhood, environment, essential elements, correlation coefficient.