Trace Elements in Medicine (Moscow)
2018, 19(3): 31-36
ORIGINAL PAPERS

SPECIAL ASPECTS OF MICROELEMENT COMPOSITION OF THE BONE TISSUE IN TRANSOSSEOUS DISTRACTION OSTEOSYNTHESIS BY ILIZAROV METHOD UNDER THE CONDITIONS OF HIGH ALTITUDE

A.N. Nakoskin ¹, A.N. Erohin ², B.D. Isakov ³, O.P. Ajsuvakova ¹

¹ All-Russian Research Institute of Medicinal and Aromatic Plants, Grina str. 7/1, Moscow, 117216, Russia
² Russian Research Center «Academician G.A. Ilizarov Restorative Traumatology and Orthopedy of Ministry of Health and Social Development of the Russian Federation, M. Ulyanova str. 6, Kurgan, 640014, Russia
³ I.K. Akhunbaev Kyrgyz State Medical Academy, I. Akhunbaeva str. 92, Bishkek, 720020, Kyrgyzstan

DOI: 10.19112/2413-6174-2018-19-3-31-36 

ABSTRACT. The aim of our work is to study the redistribution of the trace elements in bone distraction osteosynthesis in the conditions of high altitude. Material and Methods. The study was performed on 72 outbred dogs of both sexes at the age of 13 years weighing 1015 kg; 32 dogs were lengthened leg under lowlands conditions, elongation for another group among 32 animals were lengthened produced at the condition of high altitudes. The control group consisted of 8 healthy dogs from low mountain area. Technique of surgery used by us in research has been the standard. By atomic absorption spectrophotometer AAS 1 N (Germany) was studied trace element composition in the long bones and the distraction regenerate. Student's t-test and Wilcoxon test for unpaired samples was used for processing of the data. Results. Obtained data which testified of the calcium and microelement imbalance for transosseous distraction osteosynthesis in the high altitude conditions, which causes the functional changes in the musculoskeletal system similar clinical picture of Kashin – Beck disease. In conditions of high altitude the elongation of lone bones is cause of expressed phase changes of microelements in the emerging distraction regenerate. Conclusion. During distraction osteosynthesis in high altitude conditions phase changes of trace elements in the bone regenerate are formed, which creates the physiological prerequisites for the formation of a false joint.

KEYWORDS: distraction osteosynthesis, trace elements, high altitude.