Supplement to the journal
"Trace Elements in Medicine" (Moscow)
2021: 69-70

ASSESSMENT OF THE CONTENT OF MACRONUTRIENTS AND MELATONIN IN THE LENS OF RAT EYES AT MODELING CATARACTS

A.D. Chuprov¹, V.M. Treushnikov², S.V. Notova^3,4, S.M. Kim¹, T.V. Kazakova^3,4, O.V. Marshinskaia^3,4

¹N. Fyodorov Eye Microsurgery Federal State Institution of the Russian Ministry of Health, Orenburg, Russia
²Research and Development enterprise LLC «Reper-NN», Nizhny Novgorod, Russia
³Federal Research Centre of Biological Systems and Agrotechnologies RAS
⁴Orenburg State University

DOI: 10.19112/2413-6174-2021-S1-34 

ABSTRACT. In this study, the elemental composition of the cataract and non-cataract lenses of the eyes of rats was studied. The study was conducted on Wistar rats (n = 30), from which two groups were formed: control and experimental. The animals of the experimental group were simulated age-related cataracts using ultraviolet radiation for 6 months, after which the lenses of the eyes were taken. The chemical composition of the samples was studied using atomic emission and mass spectral analysis with inductively coupled plasma. It was revealed that with the development of cataracts, there is a decrease in the level of melatonin, as well as an imbalance of macronutrients in the lenses of the eyes, which is accompanied by an increase in the level of calcium and sodium against the background of a decrease in potassium, magnesium and phosphorus.

KEYWORDS: trace elements, melatonin, cataract.