Supplement to the journal
"Trace Elements in Medicine" (Moscow)
2021: 44-45

THE INFLUENCE OF PASSIVE SMOKING ON THE MICROELEMENT STATUS OF THE AMNIOTIC FLUID IN THE EXPERIMENT

O.V. Marshinskaia^1,2*, T.V. Kazakova^1,2, S.V. Notova^1,2, L.V. Lizyrchik^2,3

¹Federal Research Centre of Biological Systems and Agrotechnologies RAS, Orenburg, Russia
²Orenburg State University, Orenburg, Russia
³Regional Clinical Hospital №2 Perinatal Centre, Orenburg, Russia

DOI: 10.19112/2413-6174-2021-S1-21 

ABSTRACT. Trace elements are components of numerous regulatory enzymes and hormones necessary for the division and differentiation of fetal cells and their further development. In this regard, the aim of the study was to study the effect of passive smoking on the microelement status of amniotic fluid. For the experiment, 40 mature females of the Wistar line were selected, of which 2 groups were formed (control and experimental). The animals of the experimental group were exposed to passive smoking, the control group consisted of intact animals. The elemental status was assessed by studying the chemical composition of the amniotic fluid using the ICP-AES and ICP-MS methods in the laboratory of the ANO "Center for Biotic Medicine", Moscow. The study found that exposure to tobacco intoxication had an effect on the content of trace elements in the amniotic fluid. The concentration of Ca, Fe, and P in the amniotic fluid of the experimental animals was significantly lower by 20.9%, 74.2%, and 60.9%, re-spectively.

KEYWORDS: trace elements, passive smoking, amniotic fluid.