Trace Elements in Medicine (Moscow)
2021, 22(1): 3-20
TOPICAL PAPERS

VULNERABLE ELECTRICALLY CHARGED SARS-COV-2 POINTS, ELECTRIC MODEL OF THE VIRUS AND ROLE OF TRACE ELEMENTS IN ITS INACTIVATION

V.G. Kaplunenko¹, N.V. Kosinov¹, A.V. Skalny^2,3

¹ Nanomaterials and Nanotechnologies LTD, 27, st. Vasylkivska, Kiev, 03022, Ukraine
² First Sechenov Moscow State Medical University, 19c1, Bolshaya Pirogovskaya Street, Moscow, 119146, Rus-sia
³ Peoples Friendship University of Russia, 6, Mikluho-Maklaya str., Moscow, 117198, Russia

DOI: 10.19112/2413-6174-2021-22-1-3-20 

ABSTRACT. In the review article, electrically charged molecular groups on the surface of the virus were considered as targets for antiviral agents. The prospects of trace element application in a low oxidation state as antiviral agents have been shown. An electrical model of SARS-CoV-2 has been developed in the form of a multilayer structure, where each shell corresponds to electrically charged proteins on the surface of the virus. The model reveals the role of Coulomb forces in adsorption and fusion processes and makes it possible to identify vulnerabilities in the coronavirus that are sensitive to electrically charged substances and to an electric field. The mechanism of antiviral action of trace elements is disclosed, based on the suppression of electrostatic interaction of virus with the cell by neutralizing the charges on the surface of the virus and the cell. This allows the selection of oligopeptides and trace elements in low oxidation states to suppress the adsorption capacity of viruses. The special role of trace elements is that many potential targets that are inaccessible to antibodies and other large molecules are easily available to trace elements.

KEYWORDS: SARS-CoV-2 electrical model, vulnerabilities of coronavirus, Coulomb RNA injection, low-valence trace elements.