Trace Elements in Medicine (Moscow) 2016, 17(3): 48-53

STUDY OF CHEMICL ELEMETS CONTENT IN MEDICAL HERBS FROM SOUTHERN FERGHANA AND POSSIBILITIES OF THEIR USAGE IN TREATMENT OF DISEASES

P.K. Igamberdieva1, E.A. Danilova2, N.S. Osinskaya2

1 Ferghana Department of the Tashkent Medical Academy, Yangi turon str. 2, Ferghana 712000, Uzbekistan
2 Institute of Nuclear Physics at Uzbekistan Academy of Sciences, Ulugbek township, Tashkent 100214, Uzbekistan

DOI: 10.19112/2413-6174-2016-17-3-48-53 

ABSTRACT. At present, medical preparations of herbal origin, despite of grand success in synthesis of new biologically active preparations, do not lose their importance, but their assortment as well as perspective application in solving of most important questions of practical medicine are growing annually. Due to various geographical and climatic conditions, Uzbekistan is an important region of medicinal herbs. Analysis of medicinal herbs shows that application of some plants thousand years ago corresponds to results of pharmacological studies at the present scientific level. A methodology of analysis of various medicinal plants using instrumental neutron activation analysis (INAA) was elaborated. The technology of samples preparation (drying, crushing, weighing) and timing in analytical procedure were elaborated. Data on concentration of 23 elements in 40 species of medicinal herbs from South Ferghana were received. There were found the plants with elevated concentration of some elements. It was shown that maximal concentrations of calcium and magnesium found in Inula helenium L., ferrum and chromium – in Taraxacum officinale Wigg. s.l., selenium and potassium – in Tussilago farfara L., zinc and cobalt – in Matricaria recutita. On the basis of the obtained results, a classification of medicinal plants with maximal enrichment by some elements was elaborated. Besides the optimal ratios of macro and trace elements in some studied plants, the elevated concentration of inulin in Arctium tomentosum Mill. (45%) and Taraxacum officinale Wigg. s.l. (40%) was detected. This suggests a possibility of useing these plants in treatment of patients with diabetes mellitus. Essential oils, alkaloids, flavonoids and phenol complexes of vitamins in some studied plants may demonstrate antioxidant features due to C-, B-, K-vitamins, carotinoids, anthocyanins and tannins that elevate pharmacological effects of the plants. On the basis of various collections of plants from South Ferghana, it is possible to create preparations compensating deficiency of some macro and trace elements in human diets.

KEYWORDS: macro elements, trace elements, medicinal herbs, neutron activation analysis.