Версия сайта: English Russian
Trace Elements in Medicine
International scientific and practical peer-reviewed journal
Return back

IODINE STATUS AND BODY COMPOSITION INDICATORS OF OLDER PERSONS LIVING IN REPUBLIC OF SAKHA (YAKUTIA)

Download PDF

ABSTRACT. The aim of the study is to assess the iodine status and identify its possible connection with the indicators of body component composition in elderly individuals of the indigenous ethnic group of Yakutia. 

Materials and Methods. The iodine status (based on the concentration in daily urine) and its relationship with indicators of body component composition were assessed in 53 persons (46 women and 7 men) aged 61 to 95 years - indigenous residents of the Republic of Sakha (Yakutia). The iodine content in urine was determined by stripping voltammetric analysis, and the body composition was determined by using bioimpedance analysis.

Results. The results of the study showed that the median urinary iodine concentration (39.0 μg/L) was in the range of moderate micronutrient deficiency. More than 90% of the examined persons had iodine deficiency of varying degrees of severity: moderate – 50.9%, mild – 41.1%; only 7.5% of elderly individuals were adequately supplied with iodine; severe iodine deficiency was not detected. The concentration of iodine in daily urine was positively correlated (p<0.05) with the mass of lean tissue, body mineral component (BMC) and MC in bone tissue. In elderly individuals with moderate iodine deficiency, mass of lean tissue, BMC, and MC content in bone tissue were statistically significantly lower (p<0.01) than in individuals with adequate iodine supply or with mild iodine deficiency. 

Conclusion. The study substantiates the need to organize preventive measures to eliminate iodine deficiency in the elderly indigenous population of Yakutia. 

KEYWORDS: iodine, iodine concentration in daily urine, elderly people, indigenous residents of the Republic of Sakha (Yakutia), body composition indicators. 

For citation: Beketova N.А., Kosheleva O.V., Lebedeva U.M., Zhilinskaya N.V., Mikhailova G.P. Iodine status and body composition indicators of older persons living in Republic of Sakha (Yakutia). Trace elemets in medicine. 2025;26(1):31−36. DOI: 10.19112/2413-6174-2025-26-1-31-36

REFERENCES
Abdulkhabirova F.M., Bezlepkina O.B., Brovin D.N., Vadina T.A., Mel’nichenko G.A., Nagaeva E.V., Nikankina L.V., Peterkova V.A., Platonova N.M., Rybakova A.A., Soldatova T.V., Troshina E.A., Shiryaeva T.Yu. Clinical recommendations «Diseases and conditions associated with iodine deficiency». Problemy Endokrinologii. 2021; 67(3): 10–25. (In Russ.).
Gorbachev A.L. Methodological approaches to the study of iodine deficiency in the population. Vestnik Severo-Vostochnogo Gosudarstvennogo Universiteta. 2015; 23: 48–50. (In Russ.).
Dedov I.I., Sviridenko N.Yu., Gerasimov G.A., Peterkova V.A., Mitshenko B.P., Arbuzova M.I., Shishkina A.A., Bezlepkina O.B., Krasnoperov R.A., Gerasimov A.N., Mel’nichenko G.A., Veldanova M.V. [Assessment of iodine deficiency in certain regions of Russia]. Problemy Endokrinologii. 2000; 46(6): 3–7. (In Russ.).
Ivanov K.I., Shadrina O.V., Alekseeva E.Yu., Krivoshapkin V.G., Baturin A.K. Features of the actual nutrition of the population of the Republic of Sakha (Yakutia)]. Dal’nevostochniy Meditsinskiy Zhurnal. 2005; 2: 72–74. (In Russ.).
MU 31-07/04 «MVI soderzhaniya joda v pishhevykh produktakh, prodovol'stvennom syr'e, kormakh i produktakh ikh pererabotki, lekarstvennykh preparatakh, vitaminakh, BADakh, biologicheskikh ob'ektakh (mocha) metodom inversionnoj vol'tamperometrii na analizatorakh tipa TA». [MU 31-07/04 “Methodology for Measuring iodine content in food products, food raw materials, feed and processed products, medicines, vitamins, dietary supplements, biological objects (urine) by stripping voltammetric method on TA type analyzers”]. FR.1.31.2004.0116. (In Russ.).
Olesova L.D., Semenova E.I., Krivoshapkina Z.N., Efremova S.D., Egorova A.G., Sofronofa S.I., Yakovleva A.I. Nutrition of the indigenous population living in the Arctic zone of Yakutia. Profilakticheskaya Medetsina. 2019; 22(2): 76–81. (In Russ.).
Popova E.K., Arkhipova N.S. Nutrition characteristics and relationship with blood lipid profile in patients 60 years and older with hypertension, depending on ethnicity and length of residence in the North. Voprosy Pitaniya. 2015; 84(S3): 157. (In Russ.).
Puzin S.N., Pogozheva A.V., Potapov V.N. [Optimizing the nutrition of the elderly as a means of preventing premature aging]. Voprosy Pitaniya. 2018; 87(4): 69–77. (In Russ.).
Statistical Yearbook of the Republic of Sakha (Yakutia). Yakutsk: Territorial organization of the Federal State Statistics Service for the Republic of Sakha (Yakutia). 2022: 542. (In Russ.).
Topolyanskaya S.V., Eliseeva T.A., Balyasnikova N.A., Vakulenko O.N., Privalova E.A., Dvoretskiy L.I. Body composition and functional abilities of centenarians with coronary heart disease. Klinicheskaya Gerontologiya. 2021; 27(7-8): 5–12. (In Russ.).
Perrine C.G., Cogswell M.E., Swanson C.A., Sullivan K.M., Chen T.C., Carriquiry A.L., Dodd K.W., Caldwelle K.L., Wang C.Y. Comparison of population iodine estimates from 24-hour urine and timed-spot urine samples. Thyroid Off. J. Am. Thyroid Assoc. 2014; 24(4): 748–757. DOI: 10.1089/thy.2013.0404.