ABSTRACT. Women of fertile (childbearing) age, as well as young children, are the main demographic potential of the country and at the same time the most vulnerable groups of the population. The relevance of studying the elemental status of women of fertile age is due to the importance of the problem of forming a healthy generation of the country.
The study assessed the contents of the hair samples biochemistry in women of childbearing age living in the city of Magadan.
Materials and Methods. Twenty-five conditionally healthy women at the age of 20–34 as highest reproductive activity (mean age 27.28±0.23 years) participated in the survey. The inductively coupled plasma atomic emission spectrometry/mass spectrometry method was used to measure concentrations of the following twenty-five chemicals: Al, As, Be, Ca, Cd, Co, Cr, Cu, Fe, Hg, I, K, Li, Mg, Mn, Mo, Na, Ni, P, Pb, Se, Si, Sn, V, and Zn.
Results. A pronounced deficiency of thyroid-specific elements was revealed: copper (72%), calcium (40%), magnesium and zinc (24% each), cobalt and manganese (20% each), iodine and selenium (12% each). The excess of chemical elements was mild that demonstrated the environmental well-being of the region and confirmed the thesis about the formation of “northern deficiency” of elements in the body of residents. Such chemicals as arsenic, cadmium, mercury, lead, potassium, lithium, nickel and lead had no deviations from the norm.
Conclusion. To prevent the development of pathological conditions of the thyroid gland accompanied by impaired reproductive function in young women living in the northern regions of Russia, it is recommended to proactively undergo screening for the content of essential macro- and microelements in the body. In case of an identified imbalance, it is necessary to specifically adjust the elemental status using macro- and microelement supplements, as well as food products enriched with them.
KEYWORDS: macro- and microelements, imbalance, goiter endemia, women, North.
For citation: Stepanova E.M. Comparative analysis of the content of chemical elements in the hair of reproductive women living in conditions of goiter endemia. Trace elemets in medicine. 2025;26(1):23−30. DOI: 10.19112/2413-6174-2025-26-1-23-30
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