ASSESSMENT
OF THE ELEMENTAL STATUS OF PREGNANT WOMEN
WITH EXCESSIVE BODY WEIGHT LIVING IN KHMAO-YUGRA
ABSTRACT.
Unfavourable climatic factors of Khanty-Mansiysk Autonomous
Okrug - Yugra (KhMAO-Yugra) along with the imbalance of
chemical elements in water and soil, as well as low concentrations of vital
chemical elements aggravate the adaptation of the human organism to the
conditions of the North, are the basis for the development of diseases,
oxidative stress. The study of elemental status indicators in pregnant women
living in the northern region provides an opportunity to study the influence of
the external environment on health, morbidity and antioxidant defence of the
organism in order to prevent gestational complications and preserve the health
of the newborn.
The aim of the study was to investigate the indicators of
elemental status of pregnant women with excessive and normal body weight living
in Khanty-Mansi Autonomous Okrug-Yugra and to carry out their comparative
analysis.
Materials and methods. We examined 57 pregnant women: 30
with excessive and 27 with normal body weight. The concentration of bioelements
involved in the regulation of carbohydrate-fat metabolism and oxylation
processes: Ca, Mg, Zn, Cr, Fe, Mn, Cu, Se was determined in hair samples of
pregnant women by mass spectrometry.
Results. It was found that the average level
of indicators is within the reference values. At the same time, the
concentration of Ca, Mg, Zn, Cr, Cu, Se is lower in pregnant women with excess
body weight in comparison with women of normal body weight.
Conclusion. Considering the significant role of the studied elements
in carbohydrate-lipid metabolism and the formation of oxidative stress, it can
be assumed that an imbalance of bioelements in the body affects the development
of pathological conditions associated with altered metabolism. In
order to level the imbalance of bioelements, it is necessary to carry out preventive work with women aimed at increasing
compliance with the intake of vitamin-mineral complexes
at the stage of preconception preparation and during pregnancy.
KEYWORDS: pregnancy, excess body weight, trace elements.
For citation: Yakovenko S.V. Assessment
of the elemental status of pregnant women with excessive body weight living in
KhMAO-Yugra. Trace elemets in medicine.
2024;25(1):40-48. DOI:
10.19112/2413-6174-2024-25-1-40-48.