PROVISION WITH VITAMINS-ANTIOXIDANTS TO PATIENTS
WITH ARTERIAL HYPERTENSION LIVING IN THE TERRITORY
OF THE URBANIZED ARCTIC
ABSTRACT.
Purpose – to study the concentration of vitamins A, E,
D, C in blood serum in patients with arterial hypertension living in Salekhard.
Materials and Methods. We examined 57
patients with arterial hypertension aged 34-53 years, employees living in the
city of Salekhard: 27 (47,4%) men and 30 (52,6%) women. In blood serum, the
concentration of fat-soluble vitamins A and E was determined by the
fluorometric method, the concentration of vitamin D was determined by chemiluminescent
enzyme immunoassay, and the concentration of vitamin C was determined using
test kits.
Results. In addition to
vitamin A, the average values of the concentration of the studied vitamins
turned out to be less than the lower limit of physiologically optimal values:
according to the value of M and Me, respectively: vitamin E – 1,39 and 1,22
times; vitamin D – 1,81 and 1,84 times; vitamin C 1,43 and 1,31 times. Vitamin
E and C deficiency was found in 28 (49,1%) and 23 (40,4%) patients, in 9
(15,8%) – vitamin D deficiency, and in 42 (73,7%) – deficiency.
Conclusion. For arterial
hypertension, correction of the vitamin-antioxidant status is indicated, along
with traditional therapy, with the help of vitamin complexes and food products
enriched with vitamins, it is becoming increasingly important.
KEYWORDS: Arctic, arterial hypertension, oxidative stress, antioxidant vitamins.
For citation: Sharifov M.I. Provision with vitamins-antioxidants to patients with arterial hypertension living in the territory of the urbanized Arctic. Trace elemets in medicine. 2024;25(1):24-31. DOI: 10.19112/2413-6174-2024-25-1-24-31.