Trace Elements in Medicine (Moscow)
2017, 18(2): 54–55
SHORT COMMUNICATION

ON DECODING THE SYNTAX OF THE HUMAN HAIR BIOELEMENT METABOLISM

B. Momcilovic

Institute for Research and Development of the Sustainable Eco Systems, Srebrnjak 59, 10000, Zagreb, CROATIA

DOI: 10.19112/2413-6174-2017-18-2-54-55 

ABSTRACT. Human hair (HH) is a suitable long term biological indicator for assessing the nutritional status of bioelements (BioE). Every BioE has its individual biological assay sigmoid curve, and every such ogive has a distinct, central linear segment of a range of concentrations wherein the rate of BioE incorporation into the HH is in the dynamic equilibrium with the HH growth and its saturation capacity. This is adequate reference range of BioE indicating a satisfactory nutritional status or harmless environmental exposure. Concentrations below that linear range are considered deficient and those above it as excessive. New adequate/acceptable Min-Max reference range values for the HH BioE are (µg/g): Ca ♂ 290-1200, ♀ 440-4400; Zn ♂♀ 130-200; P ♂♀ 120-200; Na ♂ 84-1450, ♀ 55.6-1307; Mg ♂ 20-850, ♀ 40-450; Cu ♂ 8.50-18.95, ♀ 9.11-18.04; Al ♂ 3-39-27.74, ♀ 1.93-20.02: B ♂ 0.578-4.776, ♀ 0.434-2.570; Li ♂ 0.015-0.100, ♀0.014, 0.086; Sr ♂ 0.418-2.950, ♀ 0.846-7.260; I ♂ 0.15-1.97, ♀ 0.15-2.06; Se ♂ 0.013-0.98, ♂ 0.08-0.93; Ag ♂ 0.015-0.215, ♀ 0.024-0.695. The metabolic syntax of BioE is discussed. New hypothesis on the metabolic etiology of depression is proposed.

KEYWORDS: bioelements, interrelation, metabolism, biological indicator, human hair