TRACE ELEMENTS IN MEDICINE (MOSCOW)
2015. 16(4): 51-54
SHORT COMMUNICATIONS

MINERAL COMPOSITION OF SERUM IN PREGNANT WOMEN WITH ALCOHOL ABUSE (I AND III TRIMESTERS)

V. Skalny 1,2, A.A. Tinkov 1,2,3, E.S. Berezkina 1, E.V. Kiyaeva 4, I.E. Alidzhanova 4, E.V. Shitova 1

1 P.G. Demidov Yaroslavl State University, Sovetskaya str. 14, Yaroslavl, 150000, Russia
2 All-Russian Research Institute of Medicinal and Aromatic Plants, Grina str. 7/1, Moscow, 117216, Russia
3 Orenburg State Medical University, Sovetskaya str. 6, Orenburg, 460000, Russia
4 Orenburg State University, Pobedy str. 13, Orenburg, 460015, Russia

DOI: 10.19112/2413-6174-2015-16-4-51-54 

ABSTRACT. During pregnancy the mineral homeostasis is undergoing significant physiological changes. Alcohol abuse during pregnancy also induces an elemental imbalance, but the published data on the subject are few and contradictory. The purpose of this study was to reveal the features and to study the dynamics of macro elements concentration in blood serum of pregnant women with alcohol abuse. The analysis by mass spectrometry with inductively coupled plasma was performed to determine minerals Ca, K, Mg, Na, P in serum during the first and third trimesters of pregnancy in women with alcohol abuse and in control pregnant women. The levels of tested elements in serum of pregnant women with alcohol addiction did not differ significantly from the control. At the same time there was found a significant difference in correlations between results from the first and third trimesters. It may indicate an impairment of mineral homeostasis in women under alcohol abuse during pregnancy.

KEYWORDS: pregnancy, periods of pregnancy, alcoholism, macro elements, serum, imbalance.