ABSTRACT. The literature review analyzes the role of macro- and trace elements in the etiology and pathogenesis of osteoporosis. A brief description of osteoporosis as a nosology is given, risk groups for this disease are noted, and the relationship of individual macro- (calcium, phosphorus and magnesium) and trace (zinc, copper, manganese, fluorine, selenium and boron, aluminum, cadmium) with bone metabolism is presented. Interactions between elements and vitamins are reflected, and the role of heavy metals in the development of osteoporosis is described.
KEYWORDS: osteoporosis, macro elements, trace elements, bone tissue