ABSTRACT. The scientific literature presents numerous experimental data on the study of both antagonistic and sorption activity of representatives of the genus Bacillus sp. In our work, we carried out experimental studies to assess the degree of influence of essential elements from the group of heavy metals on the antagonistic activity of transient probiotic strains of Bacillus sp. The results of the study indicate a negative impact of excessive concentrations of metals on competitiveness indicators, characterized by a decrease in inhibitory characteristics in relation to test organisms. Fe has a positive effect on E. coli, which can hypothetically be characterized by the formation of ultradispersed metal complexes that increase the penetration of biologically active growth inhibitors through the protective mechanisms of bacterial cells.
KEYWORDS: iron, zinc, cobalt, copper, Bacillus, antibiotic productivity, E. coli, S. aureus