ABSTRACT.
As part of our research aimed at assessing physiological-adaptive mechanisms and the potential of
using probiotic strains in conditions of experimental acute intoxication with heavy metals, the key point was the study
of dynamically developing pathogenetic changes in the body of experimental animals against the background of a single
administration of cadmium at a dose of 3 mg/kg body weight. The data obtained indicate the presence of pronounced
multiorgan changes involving the hematopoietic, excretory and cardiovascular systems, as well as organs responsible
for detoxification, into the pathological process.
KEYWORDS: cadmium, acute intoxication, pathogenesis.