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Trace Elements in Medicine
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PROVISION WITH VITAMINS-ANTIOXIDANTS TO PATIENTS WITH ARTERIAL HYPERTENSION LIVING IN THE TERRITORY OF THE URBANIZED ARCTIC

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PROVISION WITH VITAMINS-ANTIOXIDANTS TO PATIENTS
WITH ARTERIAL HYPERTENSION LIVING IN THE TERRITORY
OF THE URBANIZED ARCTIC


ABSTRACT.


Purpose – to study the concentration of vitamins A, E, D, C in blood serum in patients with arterial hypertension living in Salekhard.

Materials and Methods. We examined 57 patients with arterial hypertension aged 34-53 years, employees living in the city of Salekhard: 27 (47,4%) men and 30 (52,6%) women. In blood serum, the concentration of fat-soluble vitamins A and E was determined by the fluorometric method, the concentration of vitamin D was determined by chemiluminescent enzyme immunoassay, and the concentration of vitamin C was determined using test kits.

Results. In addition to vitamin A, the average values of the concentration of the studied vitamins turned out to be less than the lower limit of physiologically optimal values: according to the value of M and Me, respectively: vitamin E – 1,39 and 1,22 times; vitamin D – 1,81 and 1,84 times; vitamin C 1,43 and 1,31 times. Vitamin E and C deficiency was found in 28 (49,1%) and 23 (40,4%) patients, in 9 (15,8%) – vitamin D deficiency, and in 42 (73,7%) – deficiency.

Conclusion. For arterial hypertension, correction of the vitamin-antioxidant status is indicated, along with traditional therapy, with the help of vitamin complexes and food products enriched with vitamins, it is becoming increasingly important.

KEYWORDS: Arctic, arterial hypertension, oxidative stress, antioxidant vitamins.

For citation: Sharifov M.I. Provision with vitamins-antioxidants to patients with arterial hypertension living in the territory of the urbanized Arctic. Trace elemets in medicine. 2024;25(1):24-31. DOI: 10.19112/2413-6174-2024-25-1-24-31.