Версия сайта: English Russian
Trace Elements in Medicine
International scientific and practical peer-reviewed journal
Return back

COMPARATIVE ANALYSIS OF TOXIC AND ESSENTIAL TRACE ELEMENT ACCUMULATION PATTERNS IN HAIR OF WOMEN FROM TVER, YAROSLAVL, AND VOLOGDA CITIES

Download PDF

A.A. Tinkov1,2*, A.L. Mazaletskaya1, T.V. Korobeinikova2,3, A.R. Grabeklis2,3, Yu.V. Zaitseva1, E.A. Flerova1, N.F. Kostina4, A.A. Stepanov4

1 P.G. Demidov Yaroslavl State University,
Sovetskaya str. 14, Yaroslavl, 150003, Russia

2 Peoples Friendship University of Russia,
Mikluho-Maklaya str. 6, Moscow, 117198, Russia

3 I.M. Sechenov First Moscow State Medical University (Sechenov University),
Trubetskaya str. 8/2, Moscow, 119991, Russia

4 ANO "Center for Biotic Medicine",
Zemlyanoy Val str., d. 46, Moscow, 105064,
Russia

 

(Download)

ABSTRACT. The objective of the present study was to assess the patterns of essential and toxic trace element accumulation in hair of employable-aged women from, Tver, Yaroslavl, and Vologda cities.

Materials and methods. A total of 411 occupationally unexposed women aged 18-60 years old were living in Tver (n = 150), Yaroslavl (n = 108), and Vologda (n = 153) were examined. Assessment of trace element content in hair was performed using inductively-coupled plasma mass-spectrometry.

Results. The obtained data demonstrate that women living in Tver are characterized by overaccumulation of arsenic, cadmium, and a trend to higher levels of mercury in hair. The examinees from Yaroslavl had high hair aluminum content and a trend to overaccumulation of tin in hair. At the same time, overaccumulation of toxic metals including aluminum, arsenic, cadmium, and lead, was observed in hair of women from Vologda. Among essential trace elements, the highest levels of iron, vanadium, and chromium were observed in subjects from Tver. Hair iron content in examinees from Yaroslavl also frequently exceeded the upper reference level. In contrast, women living in Yaroslavl and Vologda were characterized by low hair iron and copper content, being lower than the reference values for these elements. In subjects from Vologda characterized by high intensity of lead accumulation, hair zinc content inversely correlated with lead levels.

Conclusions. Women living in Tver, Yaroslavl, and Vologda are characterized by distinct patterns of toxic metal overaccumulation in parallel with increased risk of deficiency of copper and zinc. The latter may be mediated by excessive lead exposure. The observed differences in heavy metal accumulation may be associated with the functioning of various industries being anthropogenic sources of metal emissions, and therefore may contribute to development of environmental diseases.

KEYWORDS: metals; pollution; lead; biomonitoring; environmental diseases.