Trace Elements in Medicine (Moscow)
2021, 22(3): 34-40
DAILY RHYTHMS OF MACRO- AND MICROELEMENTS OF SALIVA IN CHILDREN WITH RECURRENT RESPIRATORY DISEASES
S.I. Mandrov, L.A. Zhdanova, A.V. Shishova
Federal State Budgetary Educational Institution of Higher Education "Ivanovo State Medical Academy" of the Ministry of Healthcare of the Russian Federation 8, Sheremetevsky prospect, Ivanovo, 153012, Russian Federation
ABSTRACT. The data of daily fluctuations of macro and microelements of mixed saliva in children with recurrent respiratory diseases (RRD) are presented. It was found that in children who rarely have acute respiratory diseases and children with RRD, the maximum concentration of Cu, Zn, Mn, Ca, K was observed in the daytime, and Na - at night. In children with frequent illnesses, there is a shift in the maximum excretion of Cu to the morning hours. In children with RRD, the daily mean values of the concentrations and amplitudes of fluctuations in saliva of Cu, Zn are increased compared with children who rarely suffer from acute respiratory diseases (p < 0,05), and the amplitudes of Ca and Na fluctuations are reduced (p < 0,05), which reflects the processes of searching for the optimal temporal mode of functioning of the circadian system, providing the mechanisms of compensatory-adaptive reactions. The study of the general and individual characteristics of the biological rhythms of macro and microelements will reveal new resources in terms of clarifying the causes of frequent morbidity.
KEYWORDS: mixed saliva, daily rhythm, macro-and microelements, children, recurrent respiratory diseases.* Corresponding author: A.V. Shishova E-mail: email@example.com