Trace Elements in Medicine (Moscow)
2021, 22(2): 50-58
ORIGINAL PAPERS

ELEMENTS OF THE STATUS OF FERTILIZED WOMEN LIVING IN THE NORTH OF TYUMEN REGION

T.Ya. Korchinа, V.I. Korchin, V.V. Lapenko

Khanty-Mansiysk State Medical Academy, Mira str. 40, Khanty-Mansiysk, 628011, Russia

DOI: 10.19112/2413-6174-2021-22-2-50-58 

ABSTRACT. The Yamalo-Nenets Autonomous Okrug (YNAO), which is part of the Arctic zone of the Russian Federation, is located in the north of the Tyumen region. The Khanty-Mansiysk Autonomous Okrug (KhMAO) is located to the southwest of it. The okrugs are Russia's strategic energy resource base. The climate of the YNAO is extreme, while the KhMAO is relatively acceptable. The impact on the body of unfavorable climatic and ecological factors provokes the development of oxidative stress. The enzymatic link of the antioxidant system includes trace elements Zn, Cu, Se, deficiency of Ca and Mg in the body increases susceptibility to oxida-tive stress, and excessive accumulation of Fe and Mn potentiates its development. Objective: to study the content of Fe, Mn, Ca, Mg, Cu, Zn, Se in the hair of women of fertile age living in the north of the Tyumen region. 108 women (1844 years old) were examined: 43 lived in the YNAO, and 65 in the KhMAO. The concentration of trace elements in the hair was determined by inductively coupled plasma mass spectrometry. In women of the YNAO, the excess accumulation of Fe and Mn is more than 2 times more common. Significantly lower levels of concentration in the hair Zn (p = 0,018), Se (p = 0,008), Ca (p = 0,050) in women of the YNAO were revealed in comparison with similar indicators in the examined persons of the KhMAO. In order to form a healthy generation of the country, women of fertile age living in the northern regions of the Russia, after the elemental analysis of hair, need to correct the elemental status point wise with the help of special monopreparations containing the appropriate trace elements and food products enriched with them.

KEYWORDS: Arctic, chemical elements, oxidative stress, trace elements-antioxidants.