Trace Elements in Medicine (Moscow)
2021, 22(2): 43-49
ORIGINAL PAPERS

COMPARATIVE ANALYSIS OF THE CONTENT OF MACROELE-MENTS AND MICROELEMENTS IN BIOLOGICAL SAMPLES OF PA-TIENTS WHO COMPLETED THERAPY FOR MALIGNANT NEOP-LASMS

E.V. Zhukovskaya¹, A.A. Nor², A.F. Karelin¹

¹ National Medical Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev Ministry of Health of the Russian Federation, Samory Mashela str.1, 117997, Moscow, Russia
² I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya str. 8/2, 119048, Moscow, Russia

DOI: 10.19112/2413-6174-2021-22-5-43-49 

ABSTRACT. The relevance of studying the content of macro and microelements in children with various malignant neoplasms is due to their high social significance, growing morbidity in all age groups. Considering the possible role of trace elements in carcinogenesis, the number of studies in the field of trace elementology is growing. The aim of this pilot study is to determine the content of macro and microelements in biological samples from patients cured of malignant neoplasms. Materials and methods. The research was carried out at the "Russian Field" Medical and Rehabilitation Research Center. All patients were in remission of acute lymphoblastic leukemia and lymphomas, ICD disease codes C 91 and C 8184. Research and control groups were formed. The results revealed deviations in the content of most of the tested micro and macro elements. Conclusion The most significant is the surplus of certain essential microelements and macroelements K, Ca, P, Zn, Se, Fe, Cu in patients who completed PT compared with the control group. At the same time, there is a deficiency of such vital trace elements as Se.

KEYWORDS: content of macro- and microelements, leukemia, lymphomas, children.